Basic Science/Physiology Research

Philip Starr Lab

The Starr Lab seeks to understand the neural basis for specific signs and symptoms of brain network disorders, including Parkinson’s disease, isolated dystonia, essential tremor, and Huntington’s disease. 

Doris Wang Lab

The Wang Lab investigates the brain network physiology of patients with movement disorders including Parkinson’s disease, isolated dystonia, and essential tremor. 

Simon Little Lab

The Little Lab uses intracranial and scalp recordings of brain signals in patients to understand the fundamental neural physiology of movement, motivation and sleep in patients with movement disorders. 

Robert Edwards Lab

The Edwards Lab studies the synaptic basis of behavior.  The nervous system processes information at synapses, specialized sites of communication between neurons.

Ken Nakamura Lab

The Nakamura Lab aims to gain insight into the normal physiology of mitochondria and glucose metabolism in the brain, and to understand how disrupting mitochondrial function and metabolism contributes to neurodegenerative diseases.

Alexandra Nelson Lab

The Nelson Lab is interested in understanding the cellular and circuit basis of motor control, particularly in the context of movement disorders such as Parkinson’s Disease and Dystonia. 

 

List of Research Projects

Fabrication of Permanent Cortical Paddles for Bidirectional Interfaces
Principal Investigator: Philip Starr, MD, PhD

Neurophysiology of movement disorders using Percept
Principal Investigator: Philip Starr, MD, PhD

Uncovering the neurophysiology of motivation in Parkinson's disease
Principal Investigator: Simon Little, MBBS, PhD

A next generation sensing neural interface study for adaptive DBS in dystonia
Principal Investigator: Simon Little, MBBS, PhD

Tracking symptom fluctuations in Parkinson's disease using smartwatch technology
Principal Investigator: Simon Little, MBBS, PhD

Manipulating and Optimizing Rhythms for Enhancement of Sleep
Principal Investigator: Simon Little, MBBS, PhD

Automated Optimization of Adaptive DBS for Parkinson’s Disease
Principal Investigator: Simon Little, MBBS, PhD